Idiopathic harlequin syndrome: successful therapy with botulium toxin

A pediatric case of idiopathic Harlequin syndrome

Harlequin syndrome, which is a rare disorder caused by dysfunction of the autonomic system, manifests as asymmetric facial flushing and sweating in response to heat, exercise, or emotional factors. The syndrome may be primary (idiopathic) with a benign course, or can occur secondary to structural abnormalities or iatrogenic factors. The precise mechanism underlying idiopathic harlequin syndrome...

Harlequin Syndrome

Postexertional harlequin syndrome with spontaneous improvement.

To cite: Emsley HCA. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200516 DESCRIPTION This man’s episodes of unilateral sweating (figure 1), flushing and piloerection started after heavy physical work moving 20 tons of gravel. Harlequin syndrome may be due to an underlying defect in the region of the thoracic sympathetic outflow as discussed in the literatur...

Harlequin Syndrome Associated with Thoracic Epidural Analgesia.

Anesthesiology, V 123 • No 5 1187 November 2015 T children who presented for surgery received thoracic epidural catheters for postoperative pain management. Postoperatively the patients were found to have unilateral facial flushing with a sharp demarcation along the midline. The rest of their physical examinations were normal. In both patients, the flushing resolved within hours of either decre...

Successful treatment of a harlequin fetus.

We report the prolonged survival of a harlequin fetus who was treated with intensive supportive measures, emollients, and oral etretinate.